SipioneLAB
UNIVERSITY OF ALBERTA
OUR LAB
We are part of a vibrant research community in the Department of Pharmacology (Faculty of Medicine and Dentistry) and at the Neuroscience and Mental Health Institute (NMHI) at the University of Alberta. We are members of the group on the Molecular and Cellular Biology of Lipids (MCBL) and of the Canadian Glycomics Network. Our multidisciplinary research approach to study neurodegeneration and Huntington's disease involves a combination of biochemical, molecular and cell biology techniques, as well as omics and in vivo studies in transgenic models.
Techniques & Approaches
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Cell culture (cell lines and primary neurons, astrocytes and microglia)
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Cell transfection
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Gene cloning and molecular biology
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Real-time PCR, RT-PCR
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Confocal microscopy/Immunocytochemistry/immunohistochemistry
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Flow cytometry
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Imaging flow cytometry
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High-content analysis microscopy
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Cell fractionation
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Protein biochemistry
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Proteomics
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In vivo studies in transgenic animals
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Animal behaviour
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Intracerebroventricular drug infusion
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Lipid analysis
Research Facilities
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Low Stress Animal Facility
Grant Support
We thank the following agencies for funding:
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Canadian Institutes of Health Research (CIHR)
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Canadian Glycomics Network
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Alberta Prion Research Institute (APRI)
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Canada Foundation for Innovation (CFI)
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Huntington Society of Canada
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Natural Sciences and Engineering Research Council of Canada (NSERC)
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SynAD
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Brain Canada
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Alberta Innovates Health Solutions
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Canada Research Chair